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Showing posts with label cytotoxic. Show all posts
Showing posts with label cytotoxic. Show all posts

Tuesday, October 13, 2015

Rodent Feeding Studies Proving Harm To Bodily Functions

I'm pleased to report that Monsanto's stock is sliding down the crapper at a fantastic speed.






Here's a tidbit from GMO Free Canada's Facebook page:


GMO Free Canada's photo.




Over 40 rodent feeding studies find harm using varieties of genetically modified foods that are on the market today (Roundup Ready or Bt toxin insecticide producing).


Harmful effects included: Stomach barrier damage, increased risk of intestinal infections, high cholesterol, high blood sugar; reproductive issues including lower birth weight and increased mortality of offspring; organ disturbances in the pancreas, liver, kidneys, adrenal glands, ovaries and testes; other disturbances including disturbances to the immune system, blood biochemistry and functioning of the digestive system.


No wonder there is no consensus on the safety of GMO foods. We need to know if it's GMO.


1. E. Abdo, et al. “Feeding Study with Bt Corn (MON810: Ajeeb YG) on Rats: Biochemical Analysis and Liver Histopathology,” Food and Nutrition Sciences, Vol. 5 No. 2, 2014, pp. 185-195.
2. Battistelli S., Baldelli B., Malatesta M. (2008), Influence of a GMO-containing diet on pancreatic acinar cells of adult mice: effects of a short-term diet reversion, “Microscopie”, 10, pp. 36-43
3. S. Battistelli, B.Citterio, B. Baldelli, C. Parlani, and M. Malatesta (2010) Histochemical and morpho-metrical study of mouse intestine epithelium after a long term diet containing genetically modified soybean Eur J Histochem. September 26;54(3): e36
4. Brasil FB, Soares LL, Faria TS, Boaventura GT, Sampaio FJ, Ramos CF.(2009) The impact of dietary organic and transgenic soy on the reproductive system of female adult rat. Anat Rec(Hoboken).292(4):587594.
5. B Cisterna, F Flach, L Vecchio, SML Barabino, S Battistelli, TE Martin, M Malatesta, M Biggiogera (2008) Can a genetically modified organism-containing diet influence embryonic development? A preliminary study on pre- implantation mouse embryos. Cisterna.Vol.52(4)
6. Joël Spiroux de Vendômois, François Roullier, Dominique Cellier, Gilles-Eric Séralini (2009) A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health Int J Biol Sci; 5(7):706-726.
7. O. P. Dolaychuk, R. S. Fedoruk (2013) Biological Effects of Different Levels of Soybeans Conventional and Transgenic Varieties in the Second-Generation Female Rats Ration. The Animal Biology, 2013, vol. 15, no. 2
8. Thanaa A. El-Kholy, Mohammad Abu Hilal, Hatim Ali Al-Abbadi, Abdulhalim Salim Serafi, Ahmad K. Al-Ghamdi, Hanan M. Sobhy and John R. C. Richardson (2014) The Effect of Extra Virgin Olive Oil and Soybean on DNA, Cytogenicity and Some Antioxidant Enzymes in Rats. Nutrients, 6(6), 2376-2386
9. El-Shamei ZS et al. Histopathological changes in some organs of male rats fed on genetically modified corn (Ajeeb YG). J Am Sci. 2012;8(10):684–696.
10. Ermakova IV (2006) Genetically modified soy leads to weight loss and increased mortality of pups of the first generation. Preliminary studies. EkosInform. Federal Environmental Law Gazette. a | -1,, p. 4-10.
11. Ermakova IV (2007) New data on the impact of GMOs on
physiological state and the higher nervous activities mammals. All-Russia Symposium TRANSGENIC PLANTS AND BIOSAFETY Moscow, October 22 - 25, pages 38-39
12. Irina Ermakova (2007) GM soybeans—revisiting a controversial format NATURE BIOTECHNOLOGY VOLUME 25 NUMBER 12 DECEMBER 1351-1354
13. Ermakova IV, IV Barskov (2008) Study of the physiological and morphological parameters in rats and their offspring using a diet containing soybean transgenic EPSPS CP4 Biological sciences. 6. p.19-20.
14. Ermakova IV (2009) Influence of soybean gene EPSPS CP4 on the physiological state and reproductive functions of rats in the first two generations Contemporary Problems in Science and Education Number 5, p.15-20. http://www.science-education.ru/33-1224
15. Finamore A, Roselli M, Britti S, Monastra G, Ambra R, Turrini A, Mengheri E. (2008) Intestinal and peripheral immune response to MON810 maize ingestion in weaning and old mice. J Agric Food Chem. Dec 10;56(23):11533-9.
16. Gab-Alla AA et al. Morphological and biochemical changes in male rats fed on genetically modified corn (Ajeeb YG). J Am Sci. 2012;8(9):1117–1123.
17. Т. V. Gorbach, I. U. Kuzminа, G. I. Gubina-Vakulik, N. G. Kolousova (2012) HORMONAL REGULATION OF SEXUAL FUNCTION AND OVARIAN HISTOLOGICAL FEATURES IN THE EXPERIMENT WITH GMO-SOYA USE IN FOOD. TAVRICHESKY LIFE SCIENCES BULLETIN 2012, Volume 15, № 2, Part 2 (58) pages 235-238
18. G.I. Gubin-Vakulik, S.A. Denisenko, T.V. Horbach, N.G. Kolousova, T.M. Popova (2012) MORPHOFUNCTIONAL STATE OF ADRENAL GLAND IN FEMALE RATS WISTAR WITH GENETICALLY MODIFIED SOY INCLUSION IN THE DIET. TAVRICHESKY LIFE SCIENCES BULLETIN 2012, Volume 15, № 3, Part 1 (59) pages 85-88
19. GI-Gubin VAKULIK TV, GORBACH BB, NG KOLOUSOVA HS, GOPKALOV (2013) THE METABOLIC AND HISTOLOGICAL CHANGES OF KIDNEYS IN FEMALE RATS AND THE FIRST GENERATION AFTER CONSUMPTION OF GENETICALLY MODIFIED SOYBEANS. SCIENTIFIC STATEMENTS Series Medicine. Pharmacy. 2013. № 11 (154). Issue 22 pages 150-155
20. G.I. Gubina-Vakulik, S.A. Denisenko, T.V. Gorbach, N.G. Kolousova, A.V. Andreev (2014) Morphofunctional Adrenal State in Adults Descendants With the Diet by Genetically Modified Soy. ЕКСПЕРИМЕНТАЛЬНА І КЛІНІЧНА МЕДИЦИНА. 2014. № 2 (63)
21. SERDAR KARAKUŞLU (2014) THE INVESTIGATION OF THE POTENTIAL EFFECTS OF GENETICALLY MODIFIED (GMO) MAIZE (Zea mays L.) ON SWISS ALBINO MICE. JUNE 2014, 25 Pages
22. Kiliç A, Akay MT. (2008) A three generation study with genetically modified Bt corn in rats: Biochemical and histopathological investigation. Food Chem Toxicol. 2008 Mar;46(3):1164-70.
23. Hasan Kiliçgün, Cebrail Gürsul, Mukadder Sunar, Gülden Gökşen (2013) The Comparative Effects of Genetically Modified Maize and Conventional Maize on Rats J Clin Anal Med ;4(2): 136-9
24. MA Konovalova, VA Blinov (2006) Influence of genetically modified soybean in mice and their offspring . Commercial Biotechnology 2006
25. Konovalova, MA, VA Blinov (2007) Morphometric parameters and features of the spectrum Blood enzymes mice receiving GENETICALLY MODIFIED SOY. All-Russia Symposium TRANSGENIC PLANTS AND BIOSAFETY Moscow, October 22 - 25, page 48
26. Konovalova MA, Potemkin EG (2007) Influence of genetically modified soybean on transport of carbohydrates in tissue.
27. Kuzmin, J. Yu, A. Kuzmin, and N. Pasieshvili (2012) Histological and Hormonal Features of Ovaries in an Experiment at Application of GMO-Soya in Nutrition. Journal of Research. 2012. № 4
28. Magaña-Gómez JA, Cervantes GL, Yepiz-Plascencia G, de la Barca AM. (2008) Pancreatic response of rats fed genetically modified soybean J Appl Toxicol. Mar;28(2):217-26.
29. Malatesta M, Caporaloni C, Gavaudan S, Rocchi MB, Serafini S, Tiberi C, Gazzanelli G. (2002) Ultrastructural morphometrical and immunocytochemical analyses of hepatocyte nuclei from mice fed on genetically modified soybean. Cell Struct Funct. Aug;27(4):173-80.
30. Manuela Malatesta, Chiara Caporaloni, Luigia Rossi, Serafina Battistelli, Marco BL Rocchi, Francesco Tonucci, and Giancarlo Gazzanelli (2002) Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean J Anat. November; 201(5): 409–415
31. Malatesta M., Biggiogera M., Manuali E., Rocchi M.B., Baldelli B., Gazzanelli G.(2003) Fine structural analysis of pancreatic acinar cell nuclei from mice fed on GM soybean. Eur J Histochem. 47,3858.
32. Malatesta M, Tiberi C, Baldelli B, Battistelli S, Manuali E, Biggiogera M. (2005) Reversibility of hepatocyte nuclear modifications in mice fed on genetically modified soybean. Eur J Histochem. Jul-Sep;49(3):237-42.
33. Malatesta M, Boraldi F, Annovi G, Baldelli B, Battistelli S, Biggiogera M, Quaglino D. (2008) A long-term study on female mice fed on a genetically modified soybean: effects on liver ageing. Histochem Cell Biol. Nov;130(5):967-77.
34. Maligin AG, Ermakova IV (2008) Soy diet suppresses reproductive function rodents. Modern problems of science and education № 6. (Annex "Biological sciences"). - C. 26
35. Nazarova AF, Ermakova IV (2010) Effect of soy diet on reproductive function and testosterone levels in rats and hamsters. Academy Trinitarism, № 77-6567, publ.15788, 12.02.
36. SG Nimbueva, R. Shirokov, SA Polyakov, SD Evgaldaev (2012) Influence of long term use of genetically modified soybeans on some morphofunctional indicators in pancreas of rats in the experiment. Articles XVII International Ecological Student Conference "Ecology Russia and adjacent territories ": in 2 volumes. Volume 2 / Novosibirsk State. Univ. Novosibirsk, 2012. Pages 119-120.
37. Oliveri et al (2006) Temporary depression of transcription in mouse preimplantation embryos from mice fed on genetically modified soybean. 48th Symposium of the Society for Histochemistry. Lake Maggiore(Italy), Sept.7- 10.
38. Hanaa ORABY, Mahrousa KANDIL, Nermeen SHAFFIE, Inas GHALY (2014) Biological impact of feeding rats with a genetically modified-based diet. Turk J Biol (2014) 38:
39. Séralini GE, Cellier D, de Vendomois JS.(2007) New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. Arch Environ Contam Toxicol. May;52(4):596-602.

40. Gilles-Eric Séralini, Emilie Clair, Robin Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin and Joël Spiroux de Vendômois (2014) Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Environmental Sciences Europe , 26:14
41. AV Surov, NY Feoktistov, MV Ushakov, AV Gureeva (2010) Changing the physiological parameters of mammals feeding genetically modified ingredients of vegetable origin. Institution of the Russian Academy of Sciences Institute of Ecology and Evolution behalf ANSevertsov RAS (IEE RAS)
42. Vecchio L, Cisterna B, Malatesta M, Martin TE, Biggiogera M. (2004) Ultrastructural analysis of testes from mice fed on genetically modified soybean. Eur J Histochem. Oct-Dec;48(4):448-54.
43. Irena M Zdziarski, John W Edwards, Judy Carman, Adrian Jones, Marni Spillanie, Ysabella Van Sebille, Julie I Haynes (2012) GM feed and its effect on the stomach mucosa of rat. 6th Australian Health and Medical Research Congress 2012
44. ZHOU Ze-wei et al. (2012) Comprehensive Evaluation on Functions & Safety of Imported GM Soybean Using BDI-GS System Soybean Science Oct. Vol. 31 No 5
‪#‎gmo‬ ‪#‎health‬ ‪#‎labelgmos‬ ‪#‎needtoknowgmo‬ ‪#‎toxic‬ ‪#‎Bttoxin‬ ‪#‎gmofreecanada‬ ‪#‎gmofreeusa‬

Friday, May 8, 2015

Get The Picture?

I met some of the people involved in MAMNYC a couple of days ago - I think the bioQUACKS are in deep trouble.

I have a great idea for them - they should appear at the UN with fruits and vegetables "malformed" by genetic engineering; for example, purple lemons, black oranges, blue lettuce...and so on. I hope they see this posting and take from it what works.

The images below are from https://www.facebook.com/GMOFreeUSA - these will make the point much better than my words:

















The last image calls for some discussion. I believe that most of us will test positive for glyphosate infection, so I wouldn't call for anyone to take this test, unless you have a lawsuit prepared. Rather, we need to determine a way to flush glyphosate and any other GMO-derived agents from our bodies.

I mentioned that I am suffering from an "incident" which had negatively affected my life for over THREE YEARS. What would be a better test to take would be a determination of the status of one's gut flora - from there we could determine the damage done to one's gastrointestinal tract. It would certainly provide me with some direction in regards to restoring my life back to a semblance of normalcy.

At any rate, let's think about May 23rd.

Thursday, January 22, 2015

New Study: Monsanto’s Herbicide Chemical Damages DNA (re-post from PatriotRising)

New Study: Monsanto’s Herbicide Chemical Damages DNA

Posted January 21, 2015 11:23 am by
Did Monsanto Know All Along?
DNA

A new peer-reviewed scientific study has found that soybean workers exposed to glyphosate suffer from DNA damage and elevated cell death. Adenine (A), cytosine (C), guanine (G), and thymine (T) are the components of nucleic acid that make up DNA, and biotech is making these important parts of our biology a mash-up that no sane person would ever want to experience.

Soybean workers in Brazil exposed to fungicides herbicides and insecticides (the main three chemical classifications used extensively by the biotech farming model) experienced an elevated level of cellular apoptosis, as well as remarkable DNA damage according to the Elsevier published, Mutation Research/Genetic Toxicology and Environmental Mutagenesis.
The research concentrated on Glyphosate and 2,4-D, two chemicals that practically cover all of the US farming landscape. Glyphosate alone is used doubly as often as it was five years ago, with more than 185 million pounds of glyphosate-based and Round Up ready chemicals sprayed on our crops annually. Most GM crops were made, in fact, to withstand Round Up chemicals specifically. (Interestingly, the USDA won’t even test for glyphosate regularly because it’s ‘too expensive.’)

The herbicide 2,4-D has been used even longer than glyphosate – since the 1940s in fact – so there is no telling just how saturated our soil, and water is with this particular chemical. (Agent Orange, used during the Vietnam war contained 2,4-D.)

Danieli Benedetti and others found that the widespread cultivation of GM soybeans in the State of Rio Grande do Sul (RS, Brazil), especially in the city of Espumoso is particularly toxic to farm workers there.

They find:

“. . .the comet assay in peripheral leukocytes and the buccal micronucleus (MN) cytome assay (BMCyt) in exfoliated buccal cells were used to assess the effects of exposures to pesticides in soybean farm workers from Espumoso.A total of 127 individuals, 81 exposed and 46 non-exposed controls, were evaluated. Comet assay and BMCyt (micronuclei and nuclear buds) data revealed DNA damage in soybean workers.

Cell death was also observed (condensed chromatin, karyorhectic, and karyolitic cells). Inhibition of non-specific choline esterase (BchE) was not observed in the workers. The trace element contents of buccal samples were analyzed by Particle-Induced X-ray Emission (PIXE). Higher concentrations of Mg, Al, Si, P, S, and Cl were observed in cells from workers. No associations with use of personal protective equipment, gender, or mode of application of pesticides were observed.


Our findings indicate the advisability of monitoring genetic toxicity in soybean farm workers exposed to pesticides.”
It isn’t just farm workers that need to be concerned, though. Research in the German journal Ithaca stumbled upon significant concentrations of glyphosate in the urine samples of city dwellers. Many of the participants in this study showed glyphosate levels in their blood and urine that were up to 20 times the allowable levels in drinking water.

Other Studies Agree – Pesticide Chemicals Damage DNA

Multiple studies prior to the Brazilian research just conducted have shown cytotoxic and DNA-damaging effects of glyphosate exposure. In one study, Koller and his colleagues found that:

“. . . lymphocytes and cells from internal organs indicate that epithelial cells are more susceptible to the cytotoxic and DNA-damaging properties of the herbicide and its formulation. Since we found genotoxic effects after short exposure to concentrations that correspond to a 450-fold dilution of spraying used in agriculture, our findings indicate that inhalation may cause DNA damage in exposed individuals.”
As Natural Society previously reported, another study found that it only takes 57 parts per million for Round Up to completely destroy human kidney cells. We kind of need our kidneys. Agricultural levels of glyphosate are often more than 200 times this level.

You have to assume Monsanto knew that its RoundUp chemicals would damage DNA. After all, they’ve hidden toxicity results before, saying that they were a ‘commercial secret.’

Approximately 92% of all soybeans grown in the US are GMO, which means they are grown with Round Up or glyphosate-containing chemicals, and the Koller study found that even smaller concentrations (.02%) of Monsanto’s best seller sprayed on our crops causes DNA damage.

That means you can dilute Round Up more than 98% and it will still damage your cells.

In what country is a company allowed to knowingly, purposefully, scientifically kill human DNA (and thus humans) and not be charged with murder, treason, or at the bare minimum the withholding of information? Oh, that’s right – America.

Sure, biotech companies will tell you that DNA gets damaged all the time – from UV rays, oxidation, medical X-rays, even environmental toxins which biotech doesn’t create, but hen they systemically market a product(s) that kills your cells – shouldn’t they be stopped?

Damaged DNA leads to cancer, faster aging, neurological disease and the break down of our organs. There are hundreds of pathological conditions which are caused by damaged DNA, not that we can’t take proactive steps to heal our DNA, but agencies which allow these products to stay on the market are an abomination.

Even 9th graders understand the importance of DNA, and while the human genome project that sequenced more than 100,00 genes stilldidn’t explain the whole picture of our genetic make-up, DNA is an essential part of it, and shouldn’t be damaged. You can revisit the basics of DNA, here.

This article originally appeared at Natural Society.